Synthesis of Biologically Potent -Aminophosphonates

ISBN-13: 9786139581573 / Angielski / Miękka / 2018 / 64 str.

Sarva Santhisudha

Opis

Amongst phosphorus compounds, aminophosphonates and their derivatives have received considerable attention in recent years because they exhibit intriguing biological activities. -aminophosphonate derivatives are gaining lot of importance in medicinal chemistry due to their applications as enzyme inhibitors, pharmacological agents , herbicides , antibiotics and inhibitors of Excitatory Post- Synaptic Potential (EPSP) synthase and HIV Protease . -Aminophosphonic acids seem to be even closer analogues of their -amino phosphonic counter parts due to their monobasic/acidic character and higher stability of the P-C bond of phosphonicacids compared with the P-O bond. Due to its medicinal importance such as anti-cancer, anti-HIV, antithrombotic and antibacterial properties, lot of reviews are needed to guide the reader into this fascinating aspect of phosphorus chemistry. This book has been initiated with this motto.

O autorze

Dr. S. Santhisudha, Department of Chemistry, Dravidian University Kuppam is a National Post-Doctoral Fellow through SERB-DST, India and a recipient of Young Scientist Award 2017 and 2016 by Venus International Foundation and A. P. Akademi of Sciences respectively. Her research interest is synthesis of bioactive organic molecules.