Neuropsychiatry and Behavioral Pharmacology

ISBN-13: 9780387973142 / Angielski / Miękka / 1990 / 353 str.

C. Thomas Gualtieri

Opis

Neuropsychiatry and Behavioral Pharmacology explores the neuropsychiatric consequences of congenital and acquired brain lesions and their appropriate pharmacologic treatment. The clinical problems addressed - practically, though always in a theoretical framework - are the severe behavioral disorders of children, of retarded people, of people with epilepsy, and of victims of traumatic brain injury. Topics examined include the neuropsychiatric and delayed neurobehavioral sequelae of traumatic brain injury, inadvertent drug effects, self-injurious behavior, Cornelia De Lange syndrome, autism, tardive dyskinesia, and childhood hyperactivity.

Spis treści

1. The Neuropsychiatric Sequelae of Traumatic Brain Injury.- The Neurobehavioral Sequelae of Traumatic Brain Injury.- The Prediction of Outcome.- The Trajectory of Recovery.- Evaluation of the TBI Patient.- 2. Delayed Neurobehavioral Sequelae of Traumatic Brain Injury.- Affective Disorders.- Delayed Amnesia.- Posttraumatic Epilepsy.- Psychosis.- Dementia.- 3. The Psychopharmacology of Traumatic Brain Injury.- Principles of Treatment.- Psychostimulants.- Amantadine.- Other Dopamine Agonists.- Antidepressants.- Lithium.- Neuroleptics.- The Psychotropic Anticonvulsants.- Benzodiazepines.- Buspirone.- Beta-Adrenergic Blockers.- Alpha Agonists.- Calcium Channel Blockers.- Opiates.- Other Neuropeptides.- Cholinergic Drugs.- Nootropes.- Cranial Electrostimulation (CES).- Examining the Patient on Psychoactive Medication.- 4. Inadvertent Drug Effects.- Licit Drugs.- Illicit Drugs.- Drugs Prescribed for Medical Reasons.- H2 Receptor Antagonists.- Sympathomimetics.- Antispasticity Drugs.- 5. Epilepsy.- Neuropsychiatric Conditions in Epileptic Patients.- Psychiatric Conditions That May Be Related to Epilepsy.- Neuropsychological and Behavioral Effects of Anticonvulsant Drugs.- Psychotropic Drugs as Convulsants and as Anticonvulsants.- 6. Neuropsychiatric Disorders in Mentally Retarded People.- Traditional Psychiatric Disorders.- Behavioral Disorders.- Pathobehavioral Mental Retardation Syndrome.- Disorders of Serotonin Regulation.- 7. Self-Injurious Behavior.- The Pharmacotherapy of SIB.- Testing the D1 Model.- The Differential Diagnosis of SIB.- 8. Behavior in the Cornelia De Lange Syndrome.- The CDLS Survey.- Contrasting Data.- Behavior in the Cornelia de Lange Syndrome.- 9. Autism.- What Is Autism?.- The Psychopharmacology of Autism.- Psychopharmacology for Autistic People.- Epilepsy.- Self-Injurious Behavior.- Aggression.- Obsessive-Compulsive Behavior.- Tourette’s Syndrome.- Abulia.- Affective Disorders.- Anxiety, Agitation, and Panic.- Psychosis and Schizophrenia.- Hyperactive or Disorganized Behavior.- The Kluver-Bucy Syndrome.- Megavitamins.- 10. Tardive Dyskinesia.- The Prevalence of Serious Neuroleptic Side Effects.- Risk Factors for Tardive Dyskinesia.- Biological Mechanisms.- Diagnosis.- Treatment.- The Course of the Disorder.- Malignant TD.- Behavioral and Cognitive Manifestations of Tardive Dyskinesia.- Neuroleptic Nonresponders.- Alternatives to Neuroleptic Treatment.- Tardive Dyskinesia Policy and Recommendations.- TMS: A System for Prevention and Control.- The Development of TMS.- 11. Three Neuropsychiatric Conditions of Childhood.- Childhood Hyperactivity.- The Kleine-Levin Syndrome.- Rheumatic Psychosis.- 12. Behavioral Psychopharmacology.- Therapeutic Trials Are Hypothesis Testing.- Theoretical Models Run in Parallel.- Behavior Is a Measurable Thing.- There Is a Personal Economy to Consider.- And a Wider Economy.- Structure.- Epilepsy Is First.- In Fever of Unknown Origin, Stop All Drugs.- Overt Toxicity Is Not a Bad Thing.- Long-Term Drugs Require Long-Term Evaluation.- Doses are Empirical.- “Yes-No” Drugs.- You Do Not Know Until You Try.- Monitoring Is No Substitute for Intelligence.- Afterword.- Appendices.- References.