Laser Systems for Photobiology and Photomedicine

ISBN-13: 9781468472899 / Angielski / Miękka / 2012 / 320 str.

Arthur N. Chester; S. Martellucci; A. M. Verga Scheggi

Opis

This volume contains the Proceedings of a two-week NATO Advanced Study Institute on "Laser Systems for Photobiology and Photomedicine," conducted from May 11 to 20, 1990 in Erice, Italy. This is the 15th annual course of the International School of Quantum Electronics (ISQE), organized under the auspices of the "Ettore Majorana" Center for Scientific Culture. The application of lasers to medicine and surgery has made amazing progress since the last ISQE Course on this subject in 1983. The present Proceedings give a tutorial introduction to today's most important areas, as well as a review of current results by leading researchers. Among the possible approaches to a NATO Advanced Study Institute on Laser Systems for Photobiology and Photomedicine, we chose to emphasize the scientific and technological aspects of advanced laser systems when applied to laboratory and clinical tests. Since it is the policy of the School to stress the advanced scientific and techn-ological achievements in the field of Quantum Electronics, the Course broadly covers performance already achieved and potential applications.

Spis treści

PHYSICAL AND BIOLOGICAL FOUNDATIONS.- Laser Photomedicine - An Overview: Past, Present, and Future.- Exogenous Chromophores for Laser Non-Surgical Photomedicine.- Modelling and Measurements of Light Propagation in Tissue for Diagnostic and Therapeutic Applications.- Chemical Laser Interactions with Human Tissues.- SURGICAL AND OPHTHALMOLOGICAL APPLICATIONS.- Mid-Infrared Laser Surgery.- The Nd:YAG Laser - Applications in Surgery.- Laser in Plastic Surgery and Dermatology.- First Experience with a Laser Clamp in Neurosurgery.- Excimer Laser Angioplasty in Human Artery Disease.- The Efficiency of Laser Panretinal Photocoagulation for Diabetes.- LOW POWER LASER THERAPY.- Effects of Visible Laser Radiation on Cultured Cells.- Medical Applications of Low Power Lasers in China.- The Use of Low Level Laser Biostimulation for the Treatment of Chronic Pain Syndromes.- PHOTODYNAMIC THERAPY: MECHANISMS AND DOSIMETRY.- Photodynamic Therapy.- Exogenous Chromophores for Laser Photosurgery (PDT).- Endoscopic Photodynamic Therapy: Clinical Aspects.- Targets and Mechanisms of Action Associated with Laser Mediated Photosensitization.- Photodynamic Therapy of Tumors: A Review of PDT Dosimetry.- PHOTODYNAMIC THERAPY: EXPERIMENTAL RESULTS.- Photodynamic Therapy Variation in Biological Activities of HPD and Biological Effectiveness with RIF-1.- A Comparison of Laser and Arc-Lamp Spectroscopic Systems for In-Vivo Pharmacokinetic Measurements of Photosensitizers Used in Photodynamic Therapy.- Experiments on Laser Mediated Photosensitization. Preclinical Evaluation of Mono-1-Aspartyl Chlorin e6 (NPe6).- Photodynamic Therapy of Tumors: Definition of PDT Dose and Response.- Laser Excited Fluorescence Lifetimes of Hematoporphyrin IX as a Function of Solution pH: Implication in Photodynamic Therapy.- Biological Applications of Time-Gated Fluorescence Spectroscopy.- Instrumentation for Photodynamic Therapy.- DIAGNOSTIC TECHNIQUES AND INSTRUMENTATION.- The Use of Optical Fibers in Biomedical Sensing.- Laser Holography as a Technique in Experimental Science.- Laser Doppler Flow Measurement for the Evaluation of Cerebral Microcirculation.- LASER SAFETY AND SYSTEM DESIGN.- Safety Issues in Laser Surgery.- Laser Surgery of the Eye: Phototoxicity Concerns.- Surgical Endoscopy Units: Room Installation.- Considerations in the Design of Medical Laser Systems and Instrumentation.- Radiation Safety of Laser Products: European and Italian Requirements.