Histone Deacetylase Inhibitors as Cancer Therapeutics: Volume 116

ISBN-13: 9780123943873 / Angielski / Twarda / 2012 / 288 str.

Steven Grant

Opis

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics."

• Provides invaluable information on the exciting and fast-moving field of cancer research
• This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics"
• Outstanding and original reviews

Spis treści

1. Histone Deacetylase Inhibitors Disrupt the Mitotic Spindle Assembly Checkpoint by Targeting Histone and Non-Histone Proteins
2. Mechanisms of Resistance to Histone Deacetylase Inhibitors
3. HDAC Inhibitors: Roles of DNA Damage and Repair
4. HDAC Inhibitor Modulation of Proteotoxicity as a Therapeutic Approach in Cancer
5. Intrinsic and Extrinsic Apoptotic Pathway Signaling as Determinants of Histone Deacetylase Inhibitor Anti-Tumor Activity
6. Histone Deacetylase Inhibitors and Rational Combination Therapies
7. HDAC Inhibitors and Chaperone Function