Genome-Wide Prediction and Analysis of Protein-Protein Functional Linkages in Bacteria

ISBN-13: 9781461447047 / Angielski / Miękka / 2012 / 60 str.

Vijaykumar Yogesh Muley; Vishal Acharya

Opis

Using genome sequencing, one can predict possible interactions among proteins. There are very few titles that focus onprotein-protein interaction predictions in bacteria. The authors willdescribe these methods and further highlight its use to predict various biological pathways andcomplexity of the cellular response to various environmental conditions. Topics include analysis of complex genome-scale protein-protein interaction networks, effects of reference genome selection on prediction accuracy, and genome sequence templates to predict protein function."

Spis treści

​Introduction.- From genomes to protein functions.- Co-evolutionary signals within genome sequences reflect functional dependence of proteins.- Chromosomal proximity of genes as an indicator of functional linkage.- Analyses of complex genome-scale biological networks.- Applications of protein interaction networks.