Functional Neural Transplantation IV: Translation to Clinical Application, Part B Volume 231

ISBN-13: 9780128138793 / Angielski / Twarda / 2017 / 316 str.

Stephen B. Dunnett; Anders Bjorklund

Opis

Functional Neural Transplantation IV: Translation to Clinical Application, Part B, Volume 231 provides the current status of cell transplantation in the nervous system, focusing on the conditions for achieving structural repair and functional recovery. New to this edition are chapters on Plasticity and Regeneration in the Injured Spinal Cord After Cell Transplantation Therapy, Transplantation of GABAergic Interneurons for Cell-Based Therapy, Rebuilding CNS Inhibitory Circuits to Control Chronic Neuropathic Pain and Itch, From Transplanting Schwann Cells in Experimental Rat Spinal Cord Injury to their Transplantation into Human Injured Spinal Cord in Clinical Trials, and the Recruitment of Endogenous CNS Stem Cells for Regeneration in Demyelinating Disease. As the fourth in a periodic series of updates at 5-7 year intervals, this volume highlights recent developments in cellular and molecular science, providing the fundamental principles of neuroplasticity and regeneration in the brain and spinal cord, while also addressing the power of pluripotent stem cells to generate new sources of precisely specified neurons for utilization in brain repair.

• Provides a comprehensive set of critical reviews covering the field
• Presents state-of-the-art topics in science and translational medicine
• Written by international leaders in the field of neural transplantation

Spis treści

1. Stem Cell Transplantation for Spinal Cord Injury Repair
Paul Lu
2. Plasticity and Regeneration in the Injured Spinal Cord After Cell Transplantation Therapy 
Satoshi Nori, Masaya Nakamura and Hideyuki Okano
3. Transplantation of GABAergic Interneurons for Cell-Based Therapy
Julien Spatazza, Walter R. Mancia Leon and Arturo Alvarez-Buylla
4. Rebuilding CNS Inhibitory Circuits to Control Chronic Neuropathic Pain and Itch
Joao M. Braz, Alex Etlin, Dina Juarez-Salinas, Ida J. Llewellyn-Smith and Allan I. Basbaum
5. From Transplanting Schwann Cells in Experimental Rat Spinal Cord Injury to their Transplantation into Human Injured Spinal Cord in Clinical Trials
Mary B. Bunge, Paula V. Monje, Aisha Khan and Patrick M. Wood
6. Recruitment of Endogenous CNS Stem Cells for Regeneration in Demyelinating Disease
Natalia A. Murphy and Robin J.M. Franklin
7. Progenitor Cell-Based Treatment of Glial Disease
Steven A. Goldman
8. Pluripotent Stem Cells and their Utility in Treating Photoreceptor Degenerations
Nozie D. Aghaizu, Kamil Kruczek, Anai Gonzalez-Cordero, Robin R. Ali and Rachael A. Pearson
9. Stem Cell-Derived Retinal Pigment Epithelium Transplantation for Treatment of Retinal Disease
Britta Nommiste, Kate Fynes, Victoria E. Tovell, Conor Ramsden, Lyndon da Cruz and Peter Coffey
10. Transplantation of Reprogrammed Neurons  for Improved Recovery After Stroke
Zaal Kokaia, Daniel Tornero and Olle Lindvall