Ex Vivo Engineering of the Tumor Microenvironment

ISBN-13: 9783319453958 / Angielski / Twarda / 2016 / 135 str.

Aamir Aref; David Barbie

Opis

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.

O autorze

Amir R. Aref, PhD, is Instructor, Dana-Farber Cancer Institute, Harvard Medical School.