Evaluation of New Lupane-Type Triterpene 'Diospyrosonate'

ISBN-13: 9783844301045 / Angielski / Miękka / 2011 / 84 str.

Vichitra Kaushik;Versha Parcha;Ratan Lal Khosa

Opis

A novel lupane-type triterpene 'Diospyrosonate' (P1) has been isolated from anti-inflammatory activity guided fractionation of petroleum ether extract precipitate of Diospyros malabarica stem bark with a gradient of ethyl acetate in petroleum ether. Further P1 was screened for anti- inflammatory activity on carrageenan and dextran induced inflammation model in rats at the dose level of 50 mg/kg body weight. Treatment of inflammed rats with P1 has showed significant reduction in inflammation caused by carrageenan (P

O autorze

KAUSHIK, VICHITRADr. Vichitra Kaushik currently working as Associate Prof in M.M.College of Pharmacy, Maharishi Markandeshwar Univ., Mullana, Ambala, Haryana, India, Dr. R L Khosa, formerly Prof and HOD Pharmacy, IT, BHU, India, Currently Director (P&D) Pharmacy, BIT, Meerut, India and Dr. Versha Parcha as Prof inDOPS, S.B.S.P.G.I., Dehradun, UK, India.