Electrospun Polymeric Nanofibers: Insight into Fabrication Techniques and Biomedical Applications

ISBN-13: 9783031314025 / Angielski

R. Jayakumar

Opis

This volume deals with the various fabrication techniques, surface functionalization and biomedical applications of polymeric fibers possessing different scale and structure. It provides an overview of fabrication techniques such as Co-axial, Centrifugal, Melt and Yarning to procure multiscale, tubular and layered fibrous scaffold employed for biomedical applications. The chapters in this volume discusse the surface/chemical functionalization of fibers which enhance the biological properties of the fibrous scaffolds as well as the development of hybrid, layered and external stimuli-responsive fibrous scaffolds that hold potential application in biosensor and other biomedical fields. In addition, recent advances and applications of polymeric multiscale fibers in tissue engineering, regenerative medicine and drug delivery are presented. The potential use of fibrous scaffolds in bone, neural, tendon/ligament and cardiac tissue engineering, nanofibers as an antimicrobial wound dressing, employed in cancer theragnostics and in the treatment of skin/periodontal infections are discussed. The volume provides expert knowledge on the fabrication techniques, development of different scale and hybrid structure fibers, surface functionalization, layered and external stimuli responsive fibrous scaffolds. It will be beneficial to material/biomaterials scientists, bioengineering and biotechnologists by providing a better understanding on the subject of the innovative applications of fibrous scaffolds in drug delivery, tissue engineering, wound dressings and regenerative medicine.

Spis treści

Recent Developments in Electrospinning Spinnertte and Collector Assembly for Biomedical Applications.- Fabrication of Multiscale Polymeric fibers for Biomedical Applications.- Coaxial Electrospun Nanofibrous Scaffolds and Its Biomedical Applications.- Melt Electrospun Nanofibers and Its Biomedical Applications.- Centrifugal Electrospun Nanofibers and Its Biomedical Applications.- Progress, Challenges and Opportunities in Electrospun Yarn-Engineered Biomaterials.- Fabrications of Textile Based Scaffolds Using Electrospun Nanofibers for Biomedical Applications.- Biomedical Applications of Electrospun Piezoelectric Nanofibrous Scaffolds.- Surface Modified Polymeric Nanofibers in Tissue Engineering and Regenerative Medicine.- Polymer/Ceramic Nanocomposite Fibers in Bone Tissue Engineering.- Electrospun Fibrous Scaffolds for Cardiac Tissue Engineering.- Electrospun Nanofibrous Scaffolds for Neural Tissue Engineering.- External Stimuli Responsive Nanofibers in Biomedical Engineering.- Electrospun Antimicrobial Polymeric Nanofibers in Wound dressings.- Application of Electrospun Polymeric Fibrous Membranes as Patches for Atopic Skin Treatments.- Nanofibrous Scaffolds for the Management of Periodontal Diseases.- Recent Advances in Brain Tumour Therapy using Electrospun Nanofibers.- Layered Fibrous Scaffolds/Membranes in Wound Healing.

O autorze

Dr. R. Jayakumar - Professor at Polymeric Biomaterials Lab, School of Nanosciences and Molecular Medicine (ACNSMM), Amrita Vishwa Vidyapeetham (University), Kochi-682041, India-specializing in the area of Polymeric Biomaterials. Dr. R. Jayakumar joined ASNSMM during November-2007. He received his Ph.D. in Polymer Chemistry from the Anna University, Chennai, India (2002). He has over 265 Journal publications, 10 book chapter and 10 patents to his credit. His publications have been cited more than 24000 times with h-index-80. In addition, he has also edited and published 7 books. Dr. Jayakumar's research laboratory at ASNSMM is mainly interested in the development of polymeric nanofibers, nanogels, nanoparticles, nanocomposite scaffolds and injectable hydrogels for tissue engineering, drug delivery and wound healing applications. He was awarded the University Postdoctoral Fellowship from Chonbuk National University (2002-2003), South Korea and FCT Postdoctoral Fellowship from the Government of Portugal (2003-2005). In addition, he was also awarded the prestigious JSPS Postdoctoral Fellowship (2005-2007) from the Japan Society for the Promotion of Science (JSPS), Japan. He has received the “Best Paper Award” from Journal of Materials Science Materials in Medicine (Springer) and IET Nanobiotechnology Journal. He received “Faculty Researcher Award-2016” from Indian Chitin and Chitosan Society and “MRSI Medal-2017” from Materials Research Society of India. He also received “India Research Excellence-Citation Awards 2017 (Health & Medical Science area)” from Clarivate Analytics, Web of Science. He was selected as a “World Top 2% Scientists from India” in “Polymers” field by Stanford University, USA in the year of 2020 & 2021. He recently received “Chancellor’s Research Excellence Award-2021” from Amrita Vishwa Vidyapeetham (University), India. He also be listed in the “Top 10 Material Science Researchers from India”. He also completed more than 20 funded projects in Polymeric Biomaterials area.