Characteristics of chronic hepatitis B e antigen-negative infection

ISBN-13: 9786206785361 / Angielski / Miękka / 88 str.

Marija Dimzova

Opis

The Republic of North Macedonia belongs to the countries with an intermediate prevalence of chronic hepatitis B virus infection. The introduction of hepatitis B vaccination into the routine vaccination calendar in 2004 has not yet shown its effects on the general population which would typically manifest as a decrease in the incidence and prevalence of HBV infection. In the Republic of North Macedonia, the HBeAg-negative form of CHB predominates. Chronic HBV infection is a dynamic process influenced by the interplay between HBV replication and the host's immune response. Due to these dynamics and the evolving nature of HBV infection, not all patients with chronic HBV infection also develop chronic hepatitis. This gives rise to the challenge of diagnosing, monitoring, and treating chronic hepatitis B patients, as well as managing associated complications such as cirrhosis, decompensated liver disease, HCC, and preventing death. There is a need to define the phases of chronic hepatitis B virus infection and evaluate the clinical, laboratory-biochemical, serological, and virological characteristics, as well as their interrelationships in patients with chronic hepatitis B.

O autorze

Associate Professor Dr. Sci. Marija Dimzova was born in 1974 in Ohrid, Republic of North Macedonia. She is a specialist in infectious diseases, and since 2002 she has been employed at the University Clinic for Infectious Diseases in Skopje. Dr. Dimzova's primary focus lies in the field of viral hepatitides.