Biomembranomics: Structure, Techniques, and Applications

ISBN-13: 9789814968614 / Twarda / 2023 / 550 str.

Hongda Wang

Opis

The membrane is a highly elaborate structure that undertakes many important biological activities, including material transport, signal transduction, energy transfer, and enzymatic reaction. This book introduces the concept of ‘omics’ into membranes and proposes the term ‘biomembranomics.’

Spis treści

1. Biomembranomics: New Concept 2. Mass Spectroscopy for Studying Biomembranomics 3. Mapping Membrane by High-Resolution Atomic Force Microscopy 4. Super-Resolution Imaging for Mapping Membrane Proteins and Saccharides 5. Fluorescence Microscopy for Studying Plasma Membrane and Intracellular Membranes 6. Single-molecule Fluorescence for Studying the Membrane Protein Dynamics and Interactions 7. Cryo-Transmission Electron Microscopy for Studying Cell Membranes 8. Cryo-Scanning Electron Microscopy for Studying Plasma Membranes 9. Infrared Spectroscopy for Studying Plasma Membrane 10. Application of Single-Molecule Force Spectroscopy in Membrane Receptors Dynamics and Signal Transduction 11. Studying Membrane Dynamics Using Force Spectroscopy Based on Atomic Force Microscopy 12. Computer Simulations to Explore Membrane Organization and Transport

O autorze

Hongda Wang has been working as a principal investigator at the Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, PRC, since 2008. He earned his bachelor’s degree from the Department of Molecular Biology at Jilin University, PRC, in 1995. He received his doctorate from the Changchun Institute of Applied Chemistry in 2000. From 2001 to 2007, he worked as a postdoctoral research associate at the Biodesign Institute at Arizona State University, USA, and served as a visiting professor there in 2008. He is also a recipient of the National Science Fund for Distinguished Young Scholars. His research focuses on studying the structure and function of cell membranes using various single-molecule techniques, particularly atomic force microscopy, molecular recognition imaging, super-resolution fluorescence microscopy, and cryo-electron microscopy.