Biomedical Application of Nanoparticles

ISBN-13: 9781498750011 / Angielski / Twarda / 2017 / 328 str.

Bertrand Rihn

Opis

This book explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human use is described, including: cellular paradigms, transcriptomics and toxicogenomics. Finally the applications of nanoparticles in medicine and antioxidant regenerative therapeutics are presented in several chapters with emphasis on how nanoparticles enhance transport of drugs across biological membrane barriers and therefore may enhance drug bioavailability.

O autorze

Bertrand Henri Rihn, MD, DSc, professor of biochemistry and molecular biol-ogy  at  Lorraine  University,  France,  is  a  leading  expert  in  the  field  of  particulate  toxicology,  with  research  topics  including  safety  toxicology,  immunotoxicology,  and investigating the transcriptomic changes in macrophages following nanopar-ticle  exposure.  In  addition  to  his  research,  Professor  Rihn  has  also  worked  as  a  clinical toxicologist, and was awarded the Baratz Award (2004) and the E. Taub Award (2011) from the National Academy of Medicine (France). He also served as the president of the French Society of Toxicology from 2007 to 2009, and was a EUROTOX Registered Toxicologist.