Anti-Idiotypes, Receptors, and Molecular Mimicry

ISBN-13: 9781461283256 / Angielski / Miękka / 2013 / 322 str.

D. Scott Linthicum; Nadir R. Farid

Opis

Here is an up-to-date review of important new methods and results in anti-idiotypes, receptors, and molecular mimicry. It begins with a discussion of the theoretical background of the anti-idiotypic network, it's role in the regulation of immune response, and the physical characteristics of anti-idiotypic antibodies. It then goes on to explore many exciting applications in such areas as insulin action, thyroid cell function, the neurosciences, cardiology, virology, pharmacology, and reproduction.

Spis treści

Idiotypes, Paratopes, and Molecular Mimicry.- Functional Heterogeneity of Anti-Idiotype Antibodies.- Comparison of the Anti-PC Response to Nominal and Idiotope Antigens.- Anti-Idiotypes as Probes of Immunoglobulin Structure.- A Molecular Recognition Code: Its Use for the Purification of ACTH, Endorphin, and LHRH Receptors.- Anti-idiotypic Antibodies and Substance P Receptors.- Anti-idiotypic Antibodies Approach to the Study of the TSH Receptor.- Mice Immunized to Insulin Develop Anti-idiotypic Antibody to the Insulin Receptor.- Molecular Characterization of Anti-Neuroleptic Idiotypes and Anti-Idiotypes.- Opiate Receptors and Molecular Shapes.- Monoclonal Antibodies to Benzodiazepines.- Idiotypy and the ?-Adrenergic Receptor.- Crime and Punishment in the Society of Lymphocytes: A Speculation on the Structure of the Putative Idiotypic Network.- Identification of Glucose Transporter Using Anti-idiotypic Antibodies, Anti-Transporter Antibodies, and Peptide Maps.- Autolmmunization Against Hormones: A New Strategy in Animal Production.- Anti-Idiotypes and Lymphokine Receptors: Interferon as a Model.- Anti-Idiotypes, Retrovirus Receptors, and an Idiotypic Network in a Model of Retrovirus-Induced Thymic Leukemia.- An Idiotype Approach for a Vaccine Against Hepatitis B Surface Antigen.- Regulation of Cell Growth and Immunity by Reovirus Anti-Receptor Antibodies.- The Production and Characterization of Anti-idiotypic Antibodies Directed Against a Monoclonal Anti-Bovine Herpesvirus I Antibody.